An Introduction to the NarrowPeaks Package: Analysis of Transcription Factor Binding ChIP-seq Data using Functional PCA
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چکیده
1 Department of Biometry and Bioinformatics, Institute of Plant Genetics, Polish Academy of Sciences, Poznan, Poland 2 Current address: Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK 3 Current address: Wellcome Trust MRC Cambridge Stem Cell Institute, Anne McLaren Laboratory for Regenerative Medicine, Department of Surgery, University of Cambridge, Cambridge, UK
منابع مشابه
An Introduction to the NarrowPeaks Package: Narrowing Down Transcription Factor Binding Site Candidates from Functional Data
State-of-the-art bioinformatic algorithms, so-called peak finders (see references [2], [5] and [8]), are used to detect transcription factor binding sites in highthroughput chromatin immunoprecipitation followed by sequencing (ChIP-seq). The data analysis is usually based on peak-search criteria of the local maxima over enriched candidate regions. For purposes of computation several assumptions...
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تاریخ انتشار 2016